Charles A. Janeway, Jr. (1943-2003)

نویسندگان

  • Kim Bottomly
  • Peter Cresswell
  • Richard A Flavell
  • Sankar Ghosh
  • Jordan S Pober
  • David G Schatz
چکیده

in Sweden under Hans Wig-zell, he joined the Yale faculty in 1977. Charlie's contributions to immunobiology have been profound. He was one of the leading immunologists of his generation, whose ideas formed many of the concepts that today comprise the basis of the field. He made major contributions to our understanding of the mechanisms whereby T cells recognize their cognate antigen. He was an important contributor to the understanding of the interactions between the T cell receptor, MHC-antigen complexes, and superantigen. Charlie coined the term " coreceptor " for CD4 and CD8 and studied the role these molecules play in T cell activation.

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منابع مشابه

Toward a Modern Synthesis of Immunity: Charles A. Janeway Jr. and the Immunologist’s Dirty Little Secret

This essay chronicles the major theoretical and experimental contributions made by Charles A. Janeway, Jr. (1943-2003), Howard Hughes Medical Institute investigator and Yale Professor of Immunobiology, who established the fundamental role of the innate immune system in the induction of the adaptive arm.

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عنوان ژورنال:
  • Cell

دوره 113  شماره 

صفحات  -

تاریخ انتشار 2003